Quantification of Howell-Jolly body-like inclusions in ganciclovir toxicity using CellaVision DM96 analyser
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چکیده
منابع مشابه
Howell-Jolly body-like inclusions in neutrophils.
A 40-year-old HIV-positive man was evaluated for fatigue, weakness, fever, and cough. He was not taking any medications. His blood count showed normocytic anemia, leukopenia, and thrombocytopenia (hemoglobin 85.0 g/L, mean corpuscular volume 99 fL, white blood cell count 1.9 109/L, platelets 50 109/L). His CD4 count was 0.05 109/L. Other laboratory tests showed normal B12, folate, thyroid, and ...
متن کاملHowell-Jolly bodies in idiopathic steatorrhoea.
Large numbers of Howell-Jolly bodies were found in the bone marrow and peripheral blood, both before and after corrective haematinic therapy, in three patients with idiopathic steatorrhoea with associated splenic atrophy, who presented with megaloblastic anaemia. The proportion of erythrocytes containing Howell-Jolly bodies was much higher in these patients when compared with the number found i...
متن کاملPrevalence of Howell-Jolly body-like inclusions in HIV patients and their correlation with CD4 counts and HIV RNA viral load.
Previous reports have described the rare occurrence of detached nuclear fragments resembling Howell-Jolly bodies within neutrophils from HIV patients, organ-transplant recipients, and patients on immunosuppressive drugs. To date, their potential clinical significance is unknown, and pathologists tend to disregard their presence. Our study sought to find a correlation between these inclusions an...
متن کامل[Automated cell recognition in hematology: CellaVision DM96 TM system].
Cellular morphology has a predominant place in diagnosis of hematological malignancies in spite of flow cytometry, cytogenetic and molecular biology progresses. CellaVisionDM8/96TM is automated microscope and image analysis software which are able to characterize white and red blood cells morphology and to perform platelets counts in peripheral blood smears. Validity of results is always submit...
متن کاملThe significance of Howell-Jolly bodies in red cell precursors.
During the routine examination of sternal marrow smears it was observed that the presence of nuclear fragments in red cell precursors, commonly known as Howell-Jolly bodies, was usually associated with clear evidence of vitamin B12 or folic acid deficiency. Moreover, this seemed to be so even when the megaloblastic transformation of erythropoiesis was not well developed. With further experience...
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ژورنال
عنوان ژورنال: British Journal of Haematology
سال: 2015
ISSN: 0007-1048
DOI: 10.1111/bjh.13784